March 2026 · Issue #14
Community Newsletter
Exposomics research, spotlights, events & resources from the exposome.cloud community
Exposomics in Focus
Exposomics Takes Center Stage at AAAS 2026 Annual Meeting
This year's AAAS Annual Meeting in Boston featured a landmark symposium on integrating exposomics into precision medicine. Researchers from seven institutions presented findings on how cumulative environmental exposures shape disease trajectories from early life through adulthood — with exposome.cloud datasets powering three of the five featured analyses. The panel underscored a growing consensus: the exposome must sit alongside the genome in clinical risk models.
Read full report →In the News
Nature Medicine
March 8, 2026
New England Journal of Medicine
March 14, 2026
Science Translational Medicine
March 19, 2026
Environmental Health Perspectives
March 21, 2026
Watch the Panel Presentations
Recorded sessions from the AAAS 2026 Exposomics Symposium — now available on-demand.
Researcher Spotlight
Dr. Thomas Hartung
Johns Hopkins Bloomberg School of Public Health
Dr. Hartung is a leading voice in toxicology and environmental health, best known for championing
the "3Rs" (Replace, Reduce, Refine) in animal testing and for developing human-relevant testing
strategies. His current work focuses on applying exposomics frameworks to assess combined chemical
exposures using advanced in vitro systems and computational toxicology.
Fun fact: Dr. Hartung has authored over 800 publications and holds honorary doctorates
on three continents — and still makes time to teach an introductory toxicology seminar every spring.
Podcast Highlights
Dr. Hartung on the Exposome Frontiers Podcast
- Why animal models systematically underestimate human chemical sensitivity
- The promise of organ-on-a-chip for high-throughput mixture testing
- How open data platforms like exposome.cloud accelerate translational research
- Regulatory barriers to adopting new approach methodologies (NAMs) in the EU and US
Featured Podcast Episode
Episode 38 · 54 min
The Chemical Mixture Problem: Why Single-Substance Limits Are Failing Us
Guests Dr. Russ Hauser (Harvard) and Dr. Luz Claudio (Mount Sinai) discuss the science and policy
gap between how we regulate chemicals individually versus how people are actually exposed —
in complex, lifelong mixtures that interact in ways no single toxicity study can capture.
Listen now
NEXUS Education
New tutorial · 22 min
Running ExWAS with the exposome.cloud Data Harmonizer
Step-by-step walkthrough: upload a multi-cohort exposure matrix, harmonize units and ontologies,
and run an environment-wide association study in the workspace.
Watch tutorial →
Exposomics Project Feature
PFAS Body Burden Calculator — v2.0
The updated PFAS Body Burden Calculator now integrates dietary, occupational, and residential
exposure pathways for 42 PFAS compounds, with probabilistic uncertainty quantification powered
by a Monte Carlo engine. Upload individual or population-level data and receive downloadable
reports with confidence intervals benchmarked to NHANES reference distributions.
Launch tool in workspace →
Exposomics In the Scientific Community
New Resource
March 17, 2026
Upcoming Events
Apr 7–9, 2026
International Exposome Society Annual Conference
Barcelona, Spain · Hybrid
Learn more →
May 12–14, 2026
NIEHS Workshop on Mixture Toxicology & Exposomics
Research Triangle Park, NC
Learn more →